Crimes of any serious sort are definitely worth protesting for extended periods. Crimes as absurd as betraying the trust of the public (e.g. the Gulf of Tonkin incident) or any of the resulting crimes (notably war crimes as in the case of the Vietnam War) are the kinds of things we should rightly protest, or even engage in civil disobedience. Obviously, my definition of what crimes are "serious" is going to be different from another person's, but it is difficult to prejudice anyone from protesting what they themselves regard to be serious crimes.
I would love to jump on a bandwagon to protest the notion that corporations deserve the same rights as individuals. The argument is made that corporations are collections of people acting in synchrony, and their rights should not disintegrate because they gather together. I could possibly support this argument in application to almost any group besides corporations because they are extremely hierarchical in nature, make decisions based solely on capital gain and grant little to no authority to the majority of their employees (blue collar or even white collar workers) and shareholders. Because of this Supreme Court ruling, corporations are granted entirely too much power in shaping national politics, as is currently being illustrated by Stephen Colbert’s "Americans for a Better Tomorrow, Tomorrow" Super PAC.
Call me cliché, but I would be willing to stage a three-week or longer protest to lower the drinking age and raise the age at which you get your driver's license. In most European countries, you are able to drink before you can drive. I am a strong believer in this theory. If you can drink before you can drive, you can also learn to drink responsibly and understand the effects alcohol has on you so you will not act stupidly and drive drunk.
I would definitely be willing to camp out in public for Bruce Springsteen tickets, but the magic of the Internet means I no longer have to. That man is a rock 'n' roll god. Sixty-two years old and still playing three-hour long concerts. Muscians half his age cannot do that. Springsteen's songs about ordinary people struggling to survive and enjoy life speaks to me and makes his music easy to identify with. Wait, was this supposed to be a political question? Uh, I will get back to you on this ...